ALPS Medical Breakthroughs ETF
ALTAR
Score™		 -1.9% info Recommen-
dation		 AVOID
2025E    2026E
P/E
ratio		 -8.2x P/Sales
ratio		 8.7x
P/BV
ratio		 73.1x Div.
yield		 0.4%


  • Description
  • Performance
  • Comps
  • premium Fundamentals
  • premium Valuation
  • premium Rating
ALPS Medical Breakthroughs ETF is an exchange-traded fund incorporated in the USA. The ETF seeks investment results that correspond generally to the performance of its underlying index, the Poliwogg Medical Breakthroughs Index (ticker symbol: PMBI).

FUND BASICS
Category US Equities
Fund Sponsor ALPS Advisors Inc
Website www.alpsetfs.com
Inception date Dec 30, 2014
Assets (mns) $89
Currency USD
Expense ratio 50 bp
Distributions Annually

FUND STRUCTURE
Regulation Open-Ended Fund
Custodian Bank of New York Mellon
Weighting Market Cap
Index replication Full
Uses derivatives No
Options available Yes

SECTOR BREAKDOWN

 


CONSTITUENT BREAKDOWN
No. of constituents 90
Wgt avg mkt cap (mns) $1,567
Large cap (>$10bn) 0.0%
Mid cap ($2-10bn) 36.9%
Small cap (<$2bn) 57.1%
Developed mkts 97.6%
Emerging mkts 2.4%

TOP TEN HOLDINGS
AXSOME THERAPEUTICS, INC. 5.0 %
ALKERMES PLC 4.7 %
VERONA PHARMA PLC 4.2 %
PTC THERAPEUTICS INC 3.6 %
ZAI LAB LTD. UNSPONSORED ADR 3.5 %
AVIDITY BIOSCIENCES INC 3.1 %
PROTAGONIST THERAPEUTICS, INC. 2.8 %
MERUS N.V. 2.7 %
CRINETICS PHARMACEUTICALS INC 2.7 %
RHYTHM PHARMACEUTICALS, INC. 2.6 %
Total 34.9 %

TOP COUNTRY EXPOSURE
UNITED STATES 66.4 %
IRELAND 5.1 %
CHINA 3.3 %
NETHERLANDS 2.7 %
SWITZERLAND 2.2 %
BRITAIN 1.6 %
BELGIUM 1.4 %
CANADA 1.0 %
CAYMAN ISLANDS 0.4 %


HISTORICAL PERFORMANCE info

  Custom date range Compare to  
  thru


Standardized Annual Returns (thru February 28)
Year-to-date 1 year 5 years 10 years Since Incep.
-5.2% -15.5% -4.0% 1.2% 2.8%

Market Correlations
versus... Beta R-squared
S&P500 0.83 24%
MSCI EAFE 0.72 19%
MSCI Emg. Mkts. 0.59 12%

Technical Indicators
Recent close $27.78
30d moving avg. $30.94
Annualized volatility 29.1%
Short interest (ETF) 0.0%
Short interest (Underlying) 9.6%
Relative strength (RSI) 40

Liquidity measures
Avg. volume (thou.) 14
Turnover 0.4%
Bid/Ask (% of price) 0.35%
ADV underlying (mns) $1,326

Distributions


FINDING ALTERNATIVE FUNDS

Below is a list of 205 potential alternatives to the ALPS Medical Breakthroughs ETF ETF based on the alternatives' overlap in portfolio holdings with SBIO. Consider funds with lower expense ratios and/or higher ALTAR Score™ ratings as possible alternatives.

Benchmark ticker: SBIO Expense: 50 bp ALTAR Score™: -1.9%


ALTERNATIVE ETFs BASED ON OVERLAP WITH SBIO
Ticker Fund
Name		 Overlap1
vs SBIO
(%)		 Expense
ratio
(bp)		 Savings
vs SBIO
(bp)		 ALTAR
Score™
(%)		 ALTAR
vs SBIO
(%)
BBC Virtus LifeSci Biotech Clinical Trials ETF 28.8 79 -29 0.0 +1.9
BBP Virtus LifeSci Biotech Products ETF 21.5 79 -29 -2.9 -1.0
IBRN iShares Neuroscience and Healthcare ETF 16.0 47 3 -2.5 -0.6
XBI SPDR S&P BIOTECH ETF 15.9 35 15 -3.3 -1.3
PSCH Invesco S&P SmallCap Health Care ETF 10.9 29 21 4.2 +6.1
PBE Invesco Biotechnology & Genome ETF 10.4 58 -8 2.2 +4.1
XPH SPDR S&P Pharmaceuticals ETF 10.0 35 15 5.0 +6.9
CANC Tema Oncology ETF 9.8 75 -25 -2.0 -0.1
PTH Invesco Dorsey Wright Healthcare Momentum ETF 9.7 60 -10 -2.9 -1.0
CNCR Range Cancer Therapeutics ETF 9.2 79 -29 0.0 +1.9
IBBQ Invesco Nasdaq Biotechnology ETF 8.0 19 31 2.1 +4.1
FFTY Innovator IBD 50 ETF 8.0 80 -30 -2.5 -0.6
IBB iShares Biotechnology ETF 7.9 45 5 0.8 +2.7
FBT First Trust NYSE Arca Biotechnology Index Fund 6.5 56 -6 5.0 +6.9
MEDX Horizon Kinetics Medical ETF 6.4 85 -35 1.9 +3.9
IDNA iShares Genomics Immunology and Healthcare ETF 6.2 47 3 -2.1 -0.2
QQQS Invesco NASDAQ Future Gen 200 ETF 6.0 20 30 -9.4 -7.5
WDNA WisdomTree BioRevolution Fund 5.8 45 5 0.0 +1.9
FMED Fidelity Disruptive Medicine ETF 5.7 50 0 -1.1 +0.8
BMED Future Health ETF 5.5 85 -35 2.5 +4.4
GURU Global X Guru Index ETF 5.4 75 -25 4.2 +6.1
IWC iShares Micro-Cap ETF 5.3 60 -10 -1.1 +0.9
LFSC F/m Emerald Life Sciences Innovation ETF 5.3 79 -29 -3.6 -1.7
GNOM Global X Genomics & Biotechnology ETF 5.2 50 0 -3.0 -1.1
FYC First Trust Small Cap Growth AlphaDEX Fund 5.1 71 -21 1.1 +3.0
HAPS Harbor Human Capital Factor US Small Cap ETF 4.9 60 -10 4.4 +6.3
IWO iShares Russell 2000 Growth ETF 4.8 24 26 1.5 +3.4
VTWG Vanguard Russell 2000 Growth ETF 4.7 15 35 1.5 +3.5
PSIL AdvisorShares Psychedelics ETF 4.7 99 -49 0.0 +1.9
HRTS Tema GLP-1 Obesity & Cardiometabolic ETF 4.5 75 -25 0.9 +2.8
MMSC First Trust Multi-Manager Small Cap Opportunities ETF 4.2 95 -45 0.7 +2.6
CAFG Pacer US Small Cap Cash Cows Growth Leaders ETF 4.2 59 -9 6.1 +8.0
MEDI Harbor Health Care ETF 3.9 80 -30 -1.6 +0.3
FTXH First Trust Nasdaq Pharmaceuticals ETF 3.6 60 -10 10.1 +12.0
IHE iShares U.S. Pharmaceuticals ETF 3.6 40 10 8.1 +10.1
CALF Pacer US Small Cap Cash Cows 100 ETF 3.4 59 -9 12.0 +13.9
RZG Invesco S&P Smallcap 600 Pure Growth ETF 3.3 35 15 3.7 +5.7
IWM iShares Russell 2000 ETF 3.2 19 31 3.6 +5.6
RSSL Global X Russell 2000 ETF 3.2 8 42 3.6 +5.5
VTWO Vanguard Russell 2000 ETF 3.1 10 40 3.8 +5.7
XSHQ Invesco S&P SmallCap Quality ETF 3.1 29 21 8.4 +10.3
BBSC JPMorgan BetaBuilders U.S. Small Cap Equity ETF 3.0 9 41 4.0 +5.9
BRNY Burney U.S. Factor Rotation ETF Burney U.S. Factor Rotation 2.9 79 -29 5.2 +7.2
PJP Invesco Pharmaceuticals ETF 2.6 57 -7 7.8 +9.7
FESM Fidelity Enhanced Small Cap ETF 2.6 28 22 3.8 +5.8
DWAS Invesco Dorsey Wright SmallCap Momentum ETF 2.5 60 -10 2.1 +4.0
GSSC Goldman Sachs Activebeta U.S. Small Cap Equity ETF 2.5 20 30 5.5 +7.5
STXK Strive Small-Cap ETF 2.4 18 32 5.5 +7.4
BKSE BNY Mellon US Small Cap Core Equity ETF 2.3 4 46 5.9 +7.8
SMMV iShares MSCI USA Small-Cap Min Vol Factor ETF 2.2 20 30 5.3 +7.2
ISCG iShares Morningstar Small-Cap Growth ETF 2.2 6 44 2.7 +4.7
FYX First Trust Small Cap Core AlphaDEX Fund 2.2 61 -11 5.9 +7.8
AFSM First Trust Active Factor Small Cap ETF 2.1 75 -25 7.0 +8.9
AVSC Avantis U.S Small Cap Equity ETF 2.0 25 25 6.6 +8.5
IJT iShares S&P Small-Cap 600 Growth ETF 1.9 18 32 5.1 +7.0
SMLF iShares U.S. SmallCap Equity Factor ETF 1.8 15 35 6.0 +7.9
VIOG Vanguard S&P Small-Cap 600 Growth ETF 1.8 15 35 5.3 +7.3
SLYG SPDR S&P 600 Small Cap Growth ETF 1.8 15 35 5.1 +7.0
OZEM Roundhill GLP-1 & Weight Loss ETF 1.8 59 -9 1.1 +3.0
SCHA Schwab U.S. Small-Cap ETF 1.7 4 46 5.3 +7.2
FLQS Franklin U.S. Small Cap Multifactor Index ETF 1.7 35 15 6.9 +8.8
NIXT Research Affiliates Deletions ETF 1.6 9 41 3.8 +5.7
PSC Principal U.S. Small-Cap ETF 1.6 38 12 6.9 +8.8
IWN iShares Russell 2000 Value ETF 1.5 24 26 5.8 +7.7
VTWV Vanguard Russell 2000 Value ETF 1.5 15 35 5.9 +7.9
ISCB iShares Morningstar Small-Cap ETF 1.5 4 46 5.6 +7.6
AGNG Global X Aging Population ETF 1.5 50 0 4.2 +6.1
ESML iShares ESG Aware MSCI USA Small-Cap ETF 1.4 17 33 5.7 +7.6
VFMO Vanguard U.S. Momentum Factor ETF 1.4 13 37 3.4 +5.3
NUSC Nuveen ESG Small-Cap ETF 1.4 31 19 5.3 +7.2
EES WisdomTree U.S. SmallCap Fund 1.4 38 12 9.1 +11.0
GRPZ Invesco S&P SmallCap 600 GARP ETF 1.4 35 15 3.1 +5.1
SAWS AAM Sawgrass US Small Cap Quality Growth ETF 1.4 55 -5 5.2 +7.1
ESIX SPDR S&P SmallCap 600 ESG ETF 1.3 12 38 5.9 +7.8
IJR iShares Core S&P Small Cap ETF 1.3 6 44 7.3 +9.2
RNSC Furst Trust Small Cap US Equity Select ETF 1.3 60 -10 6.7 +8.6
GDOC Goldman Sachs Future Health Care Equity ETF 1.3 75 -25 2.7 +4.6
ISMD Inspire Small/Mid Cap ETF 1.3 54 -4 4.7 +6.6
VBK Vanguard Small-Cap Growth ETF 1.3 7 43 1.7 +3.7
SPSM SPDR Portfolio S&P 600 Small Cap ETF 1.3 3 47 7.4 +9.3
XJR iShares ESG Screened S&P Small-Cap ETF 1.3 12 38 6.6 +8.5
TMAT Main Thematic Innovation ETF 1.2 164 -114 -1.5 +0.4
BOUT Innovator IBD Breakout Opportunities ETF 1.2 81 -31 4.8 +6.7
VIOO Vanguard S&P Small-Cap 600 ETF 1.2 10 40 7.2 +9.1
FAD First Trust Multi Cap Growth AlphaDEX Fund 1.2 64 -14 2.5 +4.5
VAMO Cambria Value & Momentum ETF 1.1 61 -11 6.8 +8.8
VXF Vanguard Extended Market ETF 1.1 6 44 4.5 +6.4
VHT Vanguard Health Care ETF 1.1 10 40 5.7 +7.7
ARKG ARK Genomic Revolution ETF 1.1 75 -25 -11.0 -9.1
ETHO Etho Climate Leadership U.S. ETF 1.1 47 3 5.5 +7.4
TINY ProShares Nanotechnology ETF 1.1 58 -8 5.8 +7.7
FHLC Fidelity MSCI Health Care Index ETF 1.0 8 42 5.9 +7.8
XSMO Invesco S&P SmallCap Momentum ETF 1.0 39 11 5.3 +7.2
PGJ Invesco Golden Dragon China ETF 1.0 70 -20 13.9 +15.8
QVMS Invesco S&P SmallCap 600 QVM Multi-factor ETF 1.0 15 35 7.3 +9.2
FPXE First Trust IPOX Europe Equity Opportunities ETF 0.9 70 -20 4.5 +6.5
FSMO Fidelity Small-Mid Cap Opportunities ETF 0.9 60 -10 6.4 +8.4
DFAS Dimensional U.S. Small Cap ETF 0.9 26 24 6.9 +8.9
PRFZ Invesco FTSE RAFI US 1500 Small-Mid ETF 0.8 39 11 4.0 +5.9
ARKK ARK Innovation ETF 0.8 75 -25 -3.3 -1.4
TPSC Timothy Plan US Small Cap Core ETF 0.8 52 -2 7.2 +9.1
OPTZ Optimize Strategy Index ETF 0.8 50 0 5.3 +7.2
LIVR Intelligent Livermore ETF 0.7 69 -19 8.2 +10.1
AVUV Avantis U.S. Small Cap Value ETF 0.7 25 25 10.8 +12.7
QLV FlexShares US Quality Low Volatility Index Fund 0.7 22 28 5.9 +7.8
USVM VictoryShares US Small Mid Cap Value Momentum ETF 0.7 25 25 7.8 +9.7
IJS iShares S&P Small-Cap 600 Value ETF 0.7 18 32 9.4 +11.4
WCEO Hypatia Women CEO ETF 0.7 85 -35 -1.3 +0.6
VFQY Vanguard U.S. Quality Factor ETF 0.7 13 37 6.6 +8.5
ISCV iShares Morningstar Small Cap Value ETF 0.7 6 44 8.4 +10.3
VIOV Vanguard S&P Small-Cap 600 Value ETF 0.7 15 35 9.3 +11.2
SLYV SPDR S&P 600 Small Cap Value ETF 0.7 15 35 9.5 +11.4
FSMD Fidelity Small-Mid Multifactor ETF 0.7 15 35 7.0 +8.9
VB Vanguard Small-Cap ETF 0.6 5 45 5.7 +7.7
JPSE JPMorgan Diversified Return U.S. Small Cap Equity ETF 0.6 29 21 7.4 +9.3
CSA VictoryShares US Small Cap Volatility Wtd ETF 0.6 35 15 4.7 +6.6
CSF VictoryShares US Discovery Enhanced Volatility Wtd ETF 0.6 42 8 5.5 +7.4
OMFS Invesco Russell 2000 Dynamic Multifactor ETF 0.6 39 11 5.4 +7.3
FNY First Trust Mid Cap Growth AlphaDEX Fund 0.6 70 -20 2.8 +4.7
GVLU Gotham 1000 Value ETF 0.6 50 0 9.1 +11.0
FNK First Trust Mid Cap Value AlphaDEX Fund 0.6 70 -20 12.3 +14.2
FNX First Trust Mid Cap Core AlphaDEX Fund 0.5 60 -10 8.2 +10.1
SFLO VictoryShares Small Cap Free Cash Flow ETF 0.5 49 1 12.7 +14.6
SIXL ETC 6 Meridian Low Beta Equity ETF 0.5 80 -30 5.8 +7.7
VIDI Vident International Equity Strategy ETF 0.5 61 -11 12.0 +13.9
JMEE JPMorgan Market Expansion Enhanced Equity ETF 0.5 24 26 7.6 +9.5
SQLV Royce Quant Small-Cap Quality Value ETF 0.5 60 -10 9.6 +11.6
HTEC ROBO Global Healthcare Technology and Innovation ETF 0.4 68 -18 2.5 +4.4
HELX Franklin Genomic Advancements ETF 0.4 50 0 0.1 +2.0
DFNV Donoghue Forlines Innovation ETF 0.4 69 -19 5.1 +7.0
GINN Goldman Sachs Innovate Equity ETF 0.4 52 -2 4.4 +6.3
KOMP SPDR S&P Kensho New Economies Composite ETF 0.4 20 30 3.7 +5.6
HART IQ Healthy Hearts ETF 0.4 45 5 6.6 +8.5
IZRL ARK Israel Innovative Technology ETF 0.4 49 1 1.4 +3.3
ONEQ Fidelity Nasdaq Composite Index ETF 0.4 21 29 4.3 +6.2
XHS SPDR S&P Health Care Services ETF 0.4 35 15 3.5 +5.4
ITEQ BlueStar Israel Technology ETF 0.4 75 -25 2.1 +4.0
TMFX Motley Fool Next Index ETF 0.4 50 0 3.2 +5.1
BBMC JPMorgan BetaBuilders U.S. Mid Cap Equity ETF 0.4 7 43 6.2 +8.2
RZV Invesco S&P Smallcap 600 Pure Value ETF 0.3 35 15 10.9 +12.8
JHSC John Hancock Multifactor Small Cap ETF 0.3 42 8 6.9 +8.8
HKND Humankind US Stock ETF 0.3 11 39 7.5 +9.4
ROUS Hartford Multifactor US Equity ETF 0.3 19 31 7.8 +9.7
SFYX SoFi Next 500 ETF 0.3 0 50 3.6 +5.5
GWX SPDR S&P International Small Cap ETF 0.3 40 10 6.7 +8.6
VFMF Vanguard U.S. Multifactor ETF 0.3 18 32 8.5 +10.4
BFOR ALPS Barron's 400 ETF 0.3 65 -15 6.2 +8.1
LQPE PEO AlphaQuest Thematic PE ETF 0.3 125 -75 6.9 +8.8
SXQG ETC 6 Meridian Quality Growth ETF 0.3 100 -50 4.6 +6.5
SMLV SPDR SSGA US Small Cap Low Volatility Index ETF 0.3 12 38 8.1 +10.0
SVAL iShares US Small Cap Value Factor ETF 0.3 20 30 11.0 +12.9
RWJ Invesco S&P SmallCap 600 Revenue ETF 0.3 39 11 9.8 +11.7
TECB iShares U.S. Tech Breakthrough Multisector ETF 0.3 40 10 4.0 +5.9
TILT FlexShares Morningstar US Market Factor Tilt Index Fund 0.2 25 25 6.0 +7.9
DEEP Roundhill Acquirers Deep Value ETF 0.2 80 -30 19.9 +21.8
EZM WisdomTree U.S. MidCap Fund 0.2 38 12 9.3 +11.2
SAGP Strategas Global Policy Opportunities ETF 0.2 65 -15 5.3 +7.2
DFAC Dimensional U.S. Core Equity 2 ETF 0.2 17 33 6.2 +8.2
DFAT Dimensional U.S. Targeted Value ETF 0.2 28 22 10.0 +12.0
ROSC Hartford Multifactor Small Cap ETF 0.2 34 16 9.0 +10.9
FAB First Trust Multi Cap Value AlphaDEX Fund 0.2 67 -17 10.1 +12.0
VALQ American Century U.S. Quality Value ETF 0.2 29 21 8.5 +10.4
VFVA Vanguard U.S. Value Factor ETF 0.2 13 37 11.7 +13.6
ITOT iShares Core S&P Total U.S. Stock Market ETF 0.1 3 47 5.3 +7.3
VTI Vanguard Total Stock Market ETF 0.1 3 47 5.3 +7.2
IWV iShares Russell 3000 ETF 0.1 20 30 5.2 +7.1
VTHR Vanguard Russell 3000 ETF 0.1 10 40 5.3 +7.2
SCHM Schwab U.S. Mid-Cap ETF 0.1 4 46 6.7 +8.6
DCOR Dimensional US Core Equity 1 ETF 0.1 14 36 5.9 +7.8
SPGM SPDR Portfolio MSCI Global Stock Market ETF 0.1 9 41 6.0 +7.9
VBR Vanguard Small Cap Value ETF 0.1 7 43 8.5 +10.4
APIE ActivePassive International Equity ETF 0.1 45 5 7.7 +9.6
SCHB Schwab U.S. Broad Market ETF 0.1 3 47 5.4 +7.4
ESGV Vanguard ESG U.S. Stock ETF 0.1 9 41 5.0 +6.9
QGRO American Century U.S. Quality Growth ETF 0.1 29 21 3.8 +5.8
DFAU Dimensional US Core Equity Market ETF 0.1 12 38 5.7 +7.6
BSVO EA Bridgeway Omni Small-Cap Value ETF 0.1 47 3 9.8 +11.7
FNDA Schwab Fundamental US Small Co. Index ETF 0.1 25 25 6.6 +8.5
IHF iShares U.S. Healthcare Providers ETF 0.1 40 10 7.0 +8.9
DFUS Dimensional U.S. Equity ETF 0.1 9 41 5.5 +7.4
AVUS Avantis U.S. Equity ETF 0.1 15 35 6.6 +8.5
FBCG Fidelity Blue Chip Growth ETF 0.1 59 -9 3.5 +5.4
VT Vanguard Total World Stock ETF 0.0 7 43 6.4 +8.3
EMCR Xtrackers Emerging Markets Carbon Reduction and Climate Impr 0.0 15 35 8.6 +10.5
TXS Texas Capital Texas Equity Index ETF 0.0 49 1 5.1 +7.0
SPDW SPDR Portfolio Developed World ex-US ETF 0.0 3 47 7.5 +9.4
ISCF iShares International SmallCap Equity Factor ETF 0.0 23 27 8.6 +10.5
FNDC Schwab Fundamental International Small Co. Index ETF 0.0 39 11 6.3 +8.2
AVSU Avantis Responsible U.S. Equity ETF 0.0 15 35 6.4 +8.3
SPTM SPDR Portfolio S&P 1500 Composite Stock Market ETF 0.0 3 47 5.7 +7.6
VLU SPDR S&P 1500 Value Tilt ETF 0.0 12 38 7.5 +9.4
AVLV Avantis U.S. Large Cap Value ETF 0.0 15 35 8.1 +10.0
AVSD Avantis Responsible International Equity ETF 0.0 23 27 6.8 +8.7
FSST Fidelity Sustainable U.S. Equity ETF 0.0 59 -9 4.4 +6.3
DFUV Dimensional US Marketwide Value ETF 0.0 22 28 8.5 +10.4
MMTM SPDR S&P 1500 Momentum Tilt ETF 0.0 12 38 4.4 +6.3
IYY iShares Dow Jones U.S. ETF 0.0 20 30 5.3 +7.2
DFSU Dimensional US Sustainability Core 1 ETF 0.0 18 32 5.8 +7.8
FELC Fidelity Enhanced Large Cap Core ETF 0.0 18 32 5.7 +7.6
AVDE Avantis International Equity ETF 0.0 23 27 8.0 +9.9
DFSV Dimensional US Small Cap Value ETF 0.0 31 19 10.9 +12.8
SCHK Schwab 1000 Index ETF 0.0 5 45 5.5 +7.4
DFEM Dimensional Emerging Markets Core Equity 2 ETF 0.0 38 12 9.9 +11.9
FNDB Schwab Fundamental US Broad Market Index ETF 0.0 25 25 7.6 +9.5
DFAE Dimensional Emerging Core Equity Market ETF 0.0 35 15 10.2 +12.1

1Overlap is the percentage of holdings by weight that are identical. For example, if Fund A has a 2% position in Apple, Inc. (AAPL) and Fund B has a 5% position, their overlapping position in AAPL is 2%.

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RESULTS & ESTIMATES

  2020 2021 2022 2023 2024 2025E 2026E
Sales per share ** ** ** ** ** ** **
Earnings per share ** ** ** ** ** ** **
Dividends per share info ** ** ** ** ** ** **
Book value per share ** ** ** ** ** ** **

 

Sales per share growth   **% **% **% **% **% **%
EPS growth   **% **% **% **% **% **%

Sales per share growth   **% **% **% **% **% **%
EPS growth   **% **% **% **% **% **%

OTHER FUNDAMENTAL METRICS

Long term EPS growth est. **%   Debt-to-equity **x
Asset turnover **%   Assets-to-equity **x

Return on equity

Revision activity*
*Six months ago = 100

Net margins

Compound annual growth rates

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VALUATION METRICS
  2024 2025E 2026E
Price-to-sales ** ** **
Price-to-earnings ** ** **
Price-to-cash flow ** ** **
Price-to-growth ** ** **
Price-to-book value ** ** **
Yield ** ** **

Historical valuation trends

Forward
multiple:		 ALPS Medical Breakthroughs ETF
Relative
to:		 S&P500 MSCI EAFE MSCI Emg. Mkts. Other ETF:

AVOID
Not worthwhile for most investors. A rating of AVOID is assigned to ETFs with ALTAR Scores in the lowest quintile (the bottom 20%) of their category. Often, funds in this category consist of stocks with little if any history or expectation of profitability, and as a result our fundamentally-driven analysis may not be relevant.

ALTAR Score™


Calculation of ALTAR Score™
Avg. Return on Equity -73.3 %
Divided by: Fwd. P/BV 51.8 x
Less: Expense ratio 50 bp
Equals: ALTAR Score -1.9 %
info More information on ALTAR Score™
MODERN PORTFOLIO THEORY info

CONSENSUS RECOMMENDATIONS: FUND CONSTITUENTS
COMPOSITE
RATING		 1.24 CATEGORY
AVERAGE		 1.58
 
The composite rating is a weighted average of analysts' consensus recommendations for individual ETF constituents, based on the following scale:

BUY = 1; OVERWEIGHT = 1.5, HOLD = 2; UNDERWEIGHT = 2.5; and SELL = 3.

Readers are cautioned that because analyst ratings tend to be inflated, the composite score may be more useful as a relative measure of sentiment between funds rather than as a stand-alone recommendation.
 

 

See RATING tab for calculation of ALTAR Score™
Risk & reward. Uses std. dev. as proxy for risk, ALTAR Score™ for return forecast.
Dividends paid by constituents to the fund. May differ from actual distributions to shareholders due to constituent changes, timing issues or other factors.
Monthly returns based on changes in price plus dividends. May differ from daily returns reported by funds. See below for standardized returns.